The Course in General Linguistics had a significant legacy within post-structuralism, notably in Derrida's deconstruction. Even though post-structuralism did not share the scientific aspirations of its predecessor, and did not seek to establish a new school of thought on the foundation of a Great Book, the Course continued to exercise an ideological function as "Saussure's work" all the same. This chapter focuses especially on Derrida's influential reception in Of Grammatology. It highlights a tension between Derrida's general critique of the civilization of the book and his exclusive reference to the volume of the Course in a deconstructive reading of Saussure's linguistics. Saussure's unpublished writing may better illustrate Derrida's call for open-ended textuality and his intellectual biography may serve as a testimony to the end of the book.